s mutane bacteria targeting by iron oxide nanoparticles

Nanoparticle targeting of Gram-positive and Gram …

2017/2/24& 0183;& 32;A variety of materials can be encapsulated into the core of the particles, such as optical dyes or iron oxide colloids, to produce imageable and magnetically active bacterial targeting constructs. As a proof-of-concept, these particles are used to bind and separate bacteria from solution in …Cited by: 20Relating the Surface Properties of Superparamagnetic Iron …2016/4/26& 0183;& 32;This study was designed to determine the effects of superparamagnetic iron oxide nanoparticles SPIONs on the biological activity of a bacterial biofilm Streptococcus mutans . Our hypothesis was that the diffusion of the SPIONs into biofilms would depend on their surface properties, which in turn would largely be determined by their surface functionality.Cited by: 22Frontiers Nano-Strategies to Fight Multidrug Resistant …Pan et al. developed a system of reduced graphene oxide rGO -iron oxide nanoparticles rGO-IONP by the chemical deposition of Fe 2 /Fe 3 ions on nanosheets of rGO in aqueous ammonia. The in vivo results showed maximum antibacterial activity due to the generation of hydroxyl radicals that can cause physical and chemical damage, which inactivated MRSA Pan et al., 2016 .Cited by: 264Nanomaterial-based therapeutics for antibiotic-resistant …2020/8/19& 0183;& 32;As the mechanisms of action of these magnetic iron oxide nanoparticles do not include killing of bacteria, this system offers a long-term antibiofilm strategy that …Cited by: 31Iron oxide magnetic nanoparticles as antimicrobials for …The use of iron oxide magnetic nanoparticles IMNP in medical and pharmaceutical areas dates to the beginning of the 1970s, as carriers. Some other uses to these nanoparticles are in vitro separation, magnetic resonance imaging and drug targeting agent. ManyCited by: 56

Effect of iron oxide and gold nanoparticles on bacterial …

2011/8/23& 0183;& 32;Iron oxide nanoparticles due to the high ionic strength frequently agglomerate in environmental and biological fluids, which shield the repulsion due to charges on the nanoparticles. Agglomeration has frequently been ignored in nanotoxicity studies, even though agglomeration would be expected to affect nanotoxicity since it changes the size, surface area, and sedimentation properties …Cited by: 185A Comparative Study of Receptor-Targeted Magnetosome …In this study, we compared two different nanoparticles that are bacterial magnetosome and HSA-coated iron oxide nanoparticles for targeting breast cancer. Both magnetosomes and HSA-coated iron oxide nanoparticles were chemically conjugated to fluorescent-labeled anti-EGFR antibodies.Cited by: 11Metal Oxide Nanoparticles: A Welcome Development for …2020/1/1& 0183;& 32;They are known to be chemically inert materials, and as a result they find appli ions in imaging, targeting, drug delivery, and biosensors. The unique properties possessed by iron oxide nanoparticles are low or no toxicity, biocompatibility, potent magnetic and .Author: Victoria Oluwaseun Fasiku, Shesan John Owonubi, Nyemaga Masanje Malima, Daniel Hassan, Neerish RevapBio-synthesized iron oxide nanoparticles for cancer …2020/8/30& 0183;& 32;Abstract. Various living organisms, such as bacteria, plants, and animals can synthesize iron oxide nanoparticles IONP . The mechanism of nanoparticle NP formation is usually described as relying on the reduction of ferric/ferrous iron ions into crystallized nanoparticulate iron that is surrounded by an organic stabilizing layer.Cited by: 5Nanoparticle-drug conjugates treating bacterial infections …2019/8/10& 0183;& 32;In a separate study, chemically synthesized iron oxide NPs with magnetic properties were coated by gentamicin which was proven to have very high antibacterial properties against various Gram-positive and negative bacteria including E. coli and S. aureus.Cited by: 14

Bacitracin-conjugated superparamagnetic iron oxide …

2012/10/8& 0183;& 32;Propargylated Fe 3 O 4 nanoparticles were then synthesized by carbodiimide reaction of propargylamine with the carboxyl groups on the surface of the iron oxide nanoparticles. By further reaction with N 3 -bacitracin in a Cu I - alyzed azide-alkyne cycloaddition, the magnetic Fe 3 O 4 nanoparticles were modified with the peptide bacitracin.Antibacterial activity of iron oxide, iron nitride, and …2020/2/18& 0183;& 32;We report bacterial inhibition by iron-oxide nominally magnetite nanoparticles NPs alone, having a mean hydrodynamic diameter of 16 nm, as well as alginate-capped iron-oxide NPs. Alginate capping increased the average hydrodynamic diameter to 230Effect of iron oxide and gold nanoparticles on bacterial …2011/8/23& 0183;& 32;Iron oxide nanoparticles due to the high ionic strength frequently agglomerate in environmental and biological fluids, which shield the repulsion due to charges on the nanoparticles. Agglomeration has frequently been ignored in nanotoxicity studies, even though agglomeration would be expected to affect nanotoxicity since it changes the size, surface area, and sedimentation properties …Frontiers Appli ion of Iron Oxide Nanoparticles in the …2020/2/28& 0183;& 32;Figure 1.The appli ion of iron oxide nanoparticles IONPs in diagnosis and treatment of Alzheimer’s disease AD . Since amyloidβ Aβ has been identified as an ideal imaging biomarker of AD at present, with the help of magnetic resonance imaging MRI , IONPs Relating the Surface Properties of Superparamagnetic Iron …2016/4/26& 0183;& 32;This study was designed to determine the effects of superparamagnetic iron oxide nanoparticles SPIONs on the biological activity of a bacterial biofilm Streptococcus mutans . Our hypothesis was that the diffusion of the SPIONs into biofilms would depend on their surface properties, which in turn would largely be determined by their surface functionality.

PhD Thesis IRON OXIDE NANOPARTICLES AND THEIR TOXICOLOGICAL EFFECTS

drug targeting, hyperthermia and magnetic resonance imaging are iron oxide s. Iron oNP xide NPs are found naturally in the environment as particulate matter in air pollution and in volcanic eruptions. Either magnetite or maghemite the two most commonlyOral biofilm elimination by combining iron-based …Therefore, the combination of iron-based nanozymes and hydrogen peroxide-generating bacteria may provide a new strategy for oral biofilm elimination in dental caries treatment. This article is part of the themed collection: Biomimetic TherapeuticsThe Effect of Gold and Iron-Oxide Nanoparticles on …Gold and iron-oxide nanoparticles are widely used in different medical appli ions, but their utilisation to eradi e biofilms on biomaterials implants is novel. Here, we studied the effect of gold and iron oxide nanoparticles on Staphylococcus aureus and Pseudomonas aeruginosa biofilms. We report that biofilm growth was reduced at higher Topical ferumoxytol nanoparticles disrupt biofilms and …2018/7/31& 0183;& 32;Zanganeh, S. et al. Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues. Nat. Nanotechnol. 11 , 986–994 2016 .Copper Nanoparticles as Antibacterial AgentsTran N, Mir A, Mallik D, Sinha A, Nayar S, et al. 2010 Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus. International J Nanomedicine 5: 277-283. Lee C, Kim JY, Lee WI, Nelson KL, Yoon J, et al. 2008 Bactericidal effect of zero-valent

Antibacterial activity of iron oxide, iron nitride, and …

2020/2/18& 0183;& 32;We report bacterial inhibition by iron-oxide nominally magnetite nanoparticles NPs alone, having a mean hydrodynamic diameter of 16 nm, as well as alginate-capped iron-oxide NPs. Alginate capping increased the average hydrodynamic diameter to 230 nm.Frontiers Nano-Strategies to Fight Multidrug Resistant …Pan et al. developed a system of reduced graphene oxide rGO -iron oxide nanoparticles rGO-IONP by the chemical deposition of Fe 2 /Fe 3 ions on nanosheets of rGO in aqueous ammonia. The in vivo results showed maximum antibacterial activity due to the generation of hydroxyl radicals that can cause physical and chemical damage, which inactivated MRSA Pan et al., 2016 .PhD Thesis IRON OXIDE NANOPARTICLES AND THEIR TOXICOLOGICAL EFFECTSdrug targeting, hyperthermia and magnetic resonance imaging are iron oxide s. Iron oNP xide NPs are found naturally in the environment as particulate matter in air pollution and in volcanic eruptions. Either magnetite or maghemite the two most commonlyNano-based drug delivery or targeting to eradi e …Passive targeting by modulating the nanoparticle structure and the physicochemical properties is an option for efficient drug delivery to the bacteria. In addition, active targeting, such as magnetic hyperthermia induced by iron oxide nanoparticles, is anotherEffects of Antifungal Carriers Based on Chitosan-Coated Iron Oxide Nanoparticles …2021/5/17& 0183;& 32;antibiotics Article Effects of Antifungal Carriers Based on Chitosan-Coated Iron Oxide Nanoparticles on Microcosm Biofilms Anne Caroline Morais Caldeir& 227;o 1, Heitor Ceolin Araujo 2, Camila Miranda Tomasella 3, Caio Sampaio 2, Marcelo Jos& 233; dos Santos Oliveira 4, Gordon Ramage 5, Juliano Pelim Pessan 2 and Douglas Roberto Monteiro 1,2,*

Silver-coated magnetic nanocomposites induce growth …

2019/11/25& 0183;& 32;Iron oxide nanoparticles have also displayed superior antibacterial activity against various pathogenic bacteria 13, while the further combination of silver and iron oxide nanoparticles …Algal Nanoparticles: Synthesis and Biotechnological …2016/6/29& 0183;& 32;Magnesium oxide MgO nanoparticles are efficient antimicrobial agent exhibiting bactericidal activity against both Gram-positive and Gram-negative bacteria, spores and viruses. The MgO NPs can be prepared from available and economical precursors.Recent development of nanomedicine for the treatment of …2020/10/14& 0183;& 32;When Fe 3 O 4 NPs were incubated in S. mutans biofilms with H 2 O 2, they can generate highly oxidative & 183;OH for bacteria killing and EPS degradation. Then, the biohybrid CARs were precisely manipulated using a magnetic field gradient to completely remove the biofilms, including dead bacteria and degraded EPS Figure 9F,G .Engineering precision nanoparticles for drug delivery …2020/12/4& 0183;& 32;Iron oxide is another commonly researched material for inorganic NP synthesis, and iron oxide NPs make up the majority of FDA A. C. and Mitragotri, S. Nanoparticles in the clinic: an update Nanoparticle biosynthesis using unicellular and …2015/8/14& 0183;& 32;The isolated MspA was docked onto the self-assembled organic thiosulfates, namely, C 19 H 27 NaO 6 S 2, C 39 H 67 NaO 8 S 2, C 39 H 69 NaO 8 S 2, C 37 H 65 NaO 8 S 2, C 59 H 107 NaO 10 S …

Antibacterial activity of iron oxide, iron nitride, and …

2020/2/18& 0183;& 32;We report bacterial inhibition by iron-oxide nominally magnetite nanoparticles NPs alone, having a mean hydrodynamic diameter of 16 nm, as well as alginate-capped iron-oxide NPs. Alginate capping increased the average hydrodynamic diameter to 230 nm.Bacteria-Carried Iron Oxide Nanoparticles for …The efficiency of maghemite nanoparticles for the treatment of anemia was sensibly higher when nanoparticles were incorporated onto the probiotic bacterium Lactobacillus fermentum MNP-bacteria than when administrated as uncoated nanoparticles MNP . Plasma iron and hemoglobin, intestine expression of divalent metal transporter 1 DMT1 and duodenal Cytochrome b DcytB , as well as …Polyacrylic Acid-Coated Iron Oxide Nanoparticles for …2014/12/8& 0183;& 32;To that end, we have developed poly acrylic acid PAA -coated iron oxide magnetite nanoparticles PAA-MNPs as efflux inhibitors and used it together with rifampicin a first line anti-TB drug on Mycobacterium smegmatis.Nano-based drug delivery or targeting to eradi e …Passive targeting by modulating the nanoparticle structure and the physicochemical properties is an option for efficient drug delivery to the bacteria. In addition, active targeting, such as magnetic hyperthermia induced by iron oxide nanoparticles, is another efficient way to …A Comparative Study of Receptor-Targeted Magnetosome …In this study, we compared two different nanoparticles that are bacterial magnetosome and HSA-coated iron oxide nanoparticles for targeting breast cancer. Both magnetosomes and HSA-coated iron oxide nanoparticles were chemically conjugated to fluorescent-labeled anti-EGFR antibodies.

BJNANO - Photothermally active nanoparticles as a …

2020/7/31& 0183;& 32;Functionalized iron oxide nanoparticles can also be used for photothermally induced bacteria eradi ion. It was demonstrated that the NIR-absorbing nanoparticles functionalized with recyclable iron oxide were capable of eliminating Gram-positive S. aureus and Gram-negative bacteria E. coli quickly and effectively 94 .Influence of interaction between surface-modified magnetic nanoparticles …of magnetic iron oxide nanoparticles MIONPs with biofilm components influences the efficacy of antibiotic treatment of an S. aureus biofilm after artificial channel digging by magne-tically propelled nanoparticles in vitro.TwoS. aureus strains will be used, withBiosynthesis of Nanoparticles by Microorganisms and …Magnetotactic bacteria synthesize intracellular magnetic particles comprising iron oxide, iron sulfides, or both 58, 59 . In order to distinguish these particles from artificially synthesized magnetic particles AMPs , they are referred to as bacterial magnetic .Nanoparticles in tissue engineering: appli ions, …2018/9/24& 0183;& 32;Furthermore, iron oxide nanoparticles have demonstrated much promise in killing post-biofilm formation in bacteria. 98 Specifically, iron oxide nanoparticles especially when functionalized with sugars such as fructose and sucrose can penetrate biofilms . 99,100Copper Nanoparticles as Antibacterial AgentsIsmail RA, Sulaiman GM, Abdulrahman SA, Marzoog TR 2015 Antibacterial activity of magnetic iron oxide nanoparticles synthesized by laser ablation in liquid. Mat Sci Eng C 53: 286-297. Lara HH, Garza-Trevi& 241;o EN, Ixtepan-Turrent L, Singh DK 2011 Silver nanoparticles are broad-spectrum bactericidal and virucidal compounds.

Polyacrylic Acid-Coated Iron Oxide Nanoparticles for …

2014/12/8& 0183;& 32;To that end, we have developed poly acrylic acid PAA -coated iron oxide magnetite nanoparticles PAA-MNPs as efflux inhibitors and used it together with rifampicin a first line anti-TB drug on Mycobacterium smegmatis.Nano-based drug delivery or targeting to eradi e …Passive targeting by modulating the nanoparticle structure and the physicochemical properties is an option for efficient drug delivery to the bacteria. In addition, active targeting, such as magnetic hyperthermia induced by iron oxide nanoparticles, is another efficient way to …BJNANO - Photothermally active nanoparticles as a …2020/7/31& 0183;& 32;Functionalized iron oxide nanoparticles can also be used for photothermally induced bacteria eradi ion. It was demonstrated that the NIR-absorbing nanoparticles functionalized with recyclable iron oxide were capable of eliminating Gram-positive S. aureus and Gram-negative bacteria E. coli quickly and effectively 94 .Progressive lysosomal membrane permeabilization …2020/5/19& 0183;& 32;In last years, iron oxide nanoparticles IONs have been extensively studied and subsequently showed deliberate applicability in different biomedical appli ions, such as magnetic cell labeling for in vitro and in vivo imaging , guided cell delivery , cell manipulation 3, 4 , gene/drug delivery 5, 6 , studies of cellular mechanics 7, 8 and magnetic resonance imaging MRI 9,10,11 .Copper Nanoparticles as Antibacterial AgentsIsmail RA, Sulaiman GM, Abdulrahman SA, Marzoog TR 2015 Antibacterial activity of magnetic iron oxide nanoparticles synthesized by laser ablation in liquid. Mat Sci Eng C 53: 286-297. Lara HH, Garza-Trevi& 241;o EN, Ixtepan-Turrent L, Singh DK 2011 Silver nanoparticles are broad-spectrum bactericidal and virucidal compounds.

Researchers use nanoparticles to break up plaque and …

2016/7/26& 0183;& 32;In that study, Gao showed that an iron oxide nanoparticle behaved similarly to a peroxidase, an enzyme found naturally that alyzes oxidative reactions, often using hydrogen peroxide. When Gao joined Koo’s lab in 2013, he proposed using these nanoparticles in an oral setting, as the oxidation of hydrogen peroxide produces free radicals that can kill bacteria.Magnetotactic Bacteria and Magnetosomes Chapter 8 … 56 Abreu, F., Cant& 227;o, M. E., Nicol& 225;s, M. F., et al., Common ancestry of iron oxide- and iron-sulfide-based biomineralization in magnetotactic bacteria. ISME J. , 5 : 10 2011 , 1634–40 . 57 Lef& 232;vre , C. T. , Trubitsyn , D. , Abreu , F. , et al. , Monophyletic origin of magnetotaxis and the first magnetosomes .Biosynthesis of magnetic nanoparticles from nano-degradation products …magnetic targeting 6–12 . The safety and efficacy of iron oxide nanoparticles, however, depend on their incorporation in the organism. Despite the fact that an exponential increase in the number of preclinical studies using magnetic nanoparticles for stem cellNanoparticles used to break up plaque and prevent …2016/7/26& 0183;& 32;They also showed that the nanoparticles' reaction with a 1 percent or less hydrogen peroxide solution was remarkably effective at killing bacteria, wiping out more than 99.9 percent of the S pH-Dependent Activity of Dextran-Coated Cerium Oxide …Cerium oxide nanoparticles or nanoceria have demonstrated great potential as antioxidants in various cell culture models. Despite such promise for reducing reactive oxygen species and an ability for surface functionalization, nanoceria has not been extensively studied for cancer appli ions to date. Herein, we engineered the surface of nanoceria with dextran and observed its activity in the

Bacteria-Carried Iron Oxide Nanoparticles for …

The efficiency of maghemite nanoparticles for the treatment of anemia was sensibly higher when nanoparticles were incorporated onto the probiotic bacterium Lactobacillus fermentum MNP-bacteria than when administrated as uncoated nanoparticles MNP . Plasma iron and hemoglobin, intestine expression of divalent metal transporter 1 DMT1 and duodenal Cytochrome b DcytB , as well as …A Comparative Study of Receptor-Targeted Magnetosome …1. Appl Biochem Biotechnol. 2018 May;185 1 :91-113. doi: 10.1007/s12010-017-2642-x. Epub 2017 Oct 30. A Comparative Study of Receptor-Targeted Magnetosome and HSA-Coated Iron Oxide Nanoparticles as MRI Contrast-Enhancing Agent in Animal Cancer Model.Frontiers Appli ion of Iron Oxide Nanoparticles in the 28/02/2020& 0183;& 32;Figure 1.The appli ion of iron oxide nanoparticles IONPs in diagnosis and treatment of Alzheimer’s disease AD . Since amyloidβ Aβ has been identified as an ideal imaging biomarker of AD at present, with the help of magnetic resonance imaging MRI , IONPs can be used for the detection of Aβ to assist in diagnosis and treatment of AD.Characterizations of magnetotactic bacteria conjugated 21/07/2017& 0183;& 32;Characterizations of magnetotactic bacteria conjugated versus unconjugated with carboxylate-Functionalized superparamagnetic iron oxide nanoparticles for tumor targeting purposes Abstract: Targeted drug delivery through the use of swimming microorganisms known as Magnetococcus marinus MC-1 magnetotactic bacteria or MTB 1 acting as Antibacterial activity of iron oxide, iron nitride, and 18/02/2020& 0183;& 32;Synthesis and characterization of nanoparticles and nanoparticle-drug conjugates. For the synthesis of iron-oxide magnetite NPs, we have adopted a two-step procedure of Park et al. , with subsequent modifi ions reported in .Step one is the synthesis of the organic carrier, which delivers the metal atoms individually to the growing lattice.

Frontiers Nano-Based Drug Delivery or Targeting to

24/04/2020& 0183;& 32;Passive targeting by modulating the nanoparticle structure and the physicochemical properties is an option for efficient drug delivery to the bacteria. In addition, active targeting, such as magnetic hyperthermia induced by iron oxide nanoparticles, is another efficient way to deliver the drugs to the targeted site.Studies on the antibacterial activity of water-soluble Abstract Increased microbial resistance being a serious issue, we synthesized iron oxide nanoparticle-encapsulated β -cyclodextrin with potential antibacterial properties. Since iron is already a biologically significant trace metal, iron and its oxides are always significant in the field of medicine. In the present study, we have successfully synthesized α -Fe2O3 nanoparticles encapsulated PhD Thesis IRON OXIDE NANOPARTICLES AND THEIR i The Applicant’s Relevant Publi ions . I. Dura Gy, Szalay B.Particle exposure through indoor environment. Nanotechnology – Toxicological Issues and Environmental Safety, Springer. 2007. pp 271-276. II. Szalay B, Kov& 225;čikova Z, Br& 243;zik M, P& 225;ndics T, T& 225;trai E. Effects of iron oxide nanoparticles on pulmonary morphology, redox system, production ofMagnetosomes: biogenic iron nanoparticles produced …22/03/2019& 0183;& 32;Thus, all research on these bacteria rises from Blakemore’s work who, without any knowledge of Bellini’s discoveries, depicted the same magnetic microorganisms in 1975 Blakemore 1975 . He described for the first time the presence of iron-rich particles within intracytoplasmic membrane vesicles, later called magnetosomes Fig. 1 .Influence of interaction between surface-modified magnetic of magnetic iron oxide nanoparticles MIONPs with biofilm components influences the efficacy of antibiotic treatment of an S. aureus biofilm after artificial channel digging by magne-tically propelled nanoparticles in vitro.TwoS. aureus strains will be used, with different ability to produce EPS.18,19 MIONPs will be made adhesive, by polymerizing

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